Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25284472 | 1.00 | SIRT2 (0.43) | SIRT2SIRT1SIRT3ALOX15TP53 | |
| SCHEMBL13050630 | 0.80 | KMT2A (0.39) | SIRT2SIRT1SIRT3TSHRKMT2A | |
| SCHEMBL1115901 | 0.77 | MAPT (0.44) | TP53TSHRKMT2AMEN1ALOX5 | |
| SCHEMBL3522910 | 0.76 | PDE4D (0.42) | TSHRKMT2AMEN1ALOX5PTGES | |
| SCHEMBL11947892 | 0.74 | CACNA1G (0.44) | SIRT2SIRT1MDM2TSHRKMT2A | |
| SCHEMBL25292403 | 0.73 | ALDH1A1 (0.42) | SIRT2SIRT1SIRT3TSHRKMT2A | |
| SCHEMBL31048564 | 0.73 | ALDH1A1 (0.42) | SIRT2SIRT1SIRT3TSHRKMT2A | |
| SCHEMBL12583956 | 0.72 | CA12 (0.42) | ALOX15TP53TSHRKMT2AMEN1 | |
| SCHEMBL25250016 | 0.71 | ALDH1A1 (0.45) | ALOX15TSHRKMT2AMEN1ALOX5 | |
| SCHEMBL27419466 | 0.71 | TSHR (0.46) | TP53TSHRKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302427-A | Fused ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |