Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617771 | 1.00 | PARP10 (0.51) | PARP10KDM4EALDH1A1NPSR1HPGD | |
| SCHEMBL27028360 | 0.84 | KDM4E (0.46) | PARP10KDM4EALDH1A1NPSR1HPGD | |
| SCHEMBL27639521 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1NPSR1HPGDPOLB | |
| SCHEMBL15527561 | 0.83 | MAPT (0.48) | KDM4EALDH1A1NPSR1HPGDPOLB | |
| SCHEMBL11206449 | 0.83 | OPRK1 (0.44) | OPRK1KCNH2TSHROPRM1RAF1 | |
| SCHEMBL2624147 | 0.82 | KDM4E (0.54) | PARP10KDM4EOPRK1KCNH2NOS1 | |
| SCHEMBL311880 | 0.81 | CYP1A2 (0.50) | KDM4EALDH1A1MAPTNOS1NOS2 | |
| SCHEMBL21623015 | 0.81 | AR (0.49) | KDM4EALDH1A1NPSR1HPGDPOLB | |
| SCHEMBL15777791 | 0.80 | HTR1A (0.47) | ALDH1A1MAPTOPRK1KCNH2TSHR | |
| SCHEMBL2540088 | 0.80 | NPC1 (0.44) | KDM4ENPSR1HPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |