Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278014 | 0.68 | MAPK1 (0.37) | ALDH1A1KMT2AMEN1HTTHSD17B10 | |
| SCHEMBL27249977 | 0.60 | POLB (0.41) | ALDH1A1KMT2AMEN1HTTHSD17B10 | |
| SCHEMBL29856316 | 0.57 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HTTHSD17B10 | |
| SCHEMBL11386180 | 0.56 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HTTHSD17B10 | |
| SCHEMBL8872820 | 0.56 | HTT (0.61) | ALDH1A1KMT2AMEN1HTTHSD17B10 | |
| SCHEMBL6718517 | 0.56 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCYP3A4RAB9A | |
| SCHEMBL10915701 | 0.55 | ALDH1A1 (0.38) | ALDH1A1HTTHSD17B10TSHRCYP3A4 | |
| SCHEMBL2937097 | 0.54 | TSHR (0.67) | ALDH1A1KMT2AMEN1HTTHSD17B10 | |
| SCHEMBL11804640 | 0.54 | PIK3R1 (0.45) | ALDH1A1HTTHSD17B10TSHRCYP3A4 | |
| SCHEMBL3665515 | 0.54 | BCHE (0.41) | ALDH1A1KMT2AMEN1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278821-B | Spiro compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | disclosed |