SCHEMBL2937097

SCHEMBL2937097

Clc1cc(Cl)c(-c2c(Cl)cc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.67
HSD17B10 Q99714 6/20 0.67
ALDH1A1 P00352 5/20 0.67
CYP3A4 P08684 5/20 0.67
RECQL P46063 3/20 0.67
AHR P35869 1/20 0.56
HPGD P15428 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CASP1 P29466 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
ALOX15 P16050 2/20 0.48
ALOX12 P18054 2/20 0.48
MAPK1 P28482 2/20 0.48
CASP7 P55210 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TTR P02766 2/20 0.48
SLC22A2 O15244 1/20 0.48
SLC22A1 O15245 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4458192 0.86 ALDH1A1 (0.59) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL4452879 0.83 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL4456478 0.83 ALDH1A1 (0.65) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL8872103 0.81 HSD17B10 (1.00) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL184648 0.81 HSD17B10 (1.00) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL4452922 0.80 ALDH1A1 (0.61) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL358001 0.78 ALDH1A1 (1.00) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL29389611 0.78 ALDH1A1 (0.50) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL4459139 0.78 ALDH1A1 (0.50) TSHRHSD17B10ALDH1A1CYP3A4RECQL
SCHEMBL11291920 0.78 HSD17B10 (0.93) TSHRHSD17B10ALDH1A1CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20210137971-A1 EDIBLE ENTEROSORBENTS USED TO MITIGATE ACUTE EXPOSURES TO INGESTIBLE ENVIRONMENTAL TOXINS FOLLOWING OUTBREAKS, NATURAL DISASTERS AND EMERGENCIES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-05-13 US disclosed
US-10551283-B2 Actively shaken in-situ passive sampling device UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) 2020-02-04 US disclosed
US-20180088008-A1 ACTIVELY SHAKEN IN-SITU PASSIVE SAMPLING DEVICE UNIVERSITY OF MARYLAND, BALTIMORE COUNTY 2018-03-29 US disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
US-6352644-B1 A METHOD FOR USING SUBCRITICAL WATER TO IMPROVE THE EFFECTIVENESS OF A DESIRED CHEMICAL PROCESS ENERGY & ENVIRONMENTAL RESEARCH CENTER FOUNDATION 2002-03-05 US disclosed
US-5403477-A Sample preparation extractor comprising composite tube of polyolefin or fluoropolymer having on interior wall carbon allotrope particles to which contaminants adhere until removed by solvent; gas or liquid chromatography THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-04-04 US disclosed
US-5389251-A Organic contaminant separator THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-02-14 US disclosed
US-5308493-A Sampling and analyzing impurities in polymer composite tubes and passing solvents, analyzing with chromatography THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-05-03 US disclosed
US-5273655-A Passing a contaminated aqueous medium through a tube of a blend of polyolefin and polyester; dissolving the adhering impurities and chromatographically analyzing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-12-28 US disclosed
US-5037553-A Adhesion to polyolefin tube; solvent removal; chromatographic analysis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1991-08-06 US disclosed
US-4276179-A Removing halogenated hydrocarbons from aqueous media by utilizing a polyolefinic microporous adsorbent CELANESE CORPORATION (US) 1981-06-30 US disclosed
US-4246255-A Disposal of PCB ROCKWELL INTERNATIONAL CORPORATION (US) 1981-01-20 US disclosed
US-4222926-A ADDING A VINYL ACETATE CO- OR TERPOLYMER TO PREVENT DRIPPING OF MELT DAINIPPON INK & CHEMICALS, INC. (JP) 1980-09-16 US disclosed
US-4110302-A MOLDING CELANESE CORPORATION (US) 1978-08-29 US disclosed