Lithium

Lithium

SCHEMBL30438304

CC1=Cc2c(cccc2-c2ccc(C(C)(C)C)cc2)C1.[Li]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
TSHR P16473 1/20 0.34
PTAFR P25105 1/20 0.34
KIF11 P52732 3/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
S1PR1 P21453 1/20 0.33
DGAT1 O75907 1/20 0.33
PARP1 P09874 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
HTR1D P28221 1/20 0.31
ADRA1A P35348 1/20 0.31
NISCH Q9Y2I1 1/20 0.31
ASIC1 P78348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1807786 0.98 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL29594761 0.98 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL29040664 0.97 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL28148566 0.97 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
Hydrochloric Acid SCHEMBL27911650 0.95 KIF11 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL27911649 0.93 BRD4 (0.34) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL26606289 0.87 NR1H2 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL29594786 0.84 RXRB (0.36) PTAFRKIF11NPC1RAB9AALDH1A1
SCHEMBL6031753 0.84 RXRB (0.36) PTAFRKIF11NPC1RAB9AALDH1A1
SCHEMBL2707579 0.83 BRD4 (0.35) BRD4CREBBPTSHRPTAFRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096763-B Polyethylene 株式会社LG化学 2024-11-19 CN disclosed
CN-116096763-A Polyethylene 株式会社LG化学 2023-05-09 CN disclosed