SCHEMBL1807786

SCHEMBL1807786

CC1=Cc2c(cccc2-c2ccc(C(C)(C)C)cc2)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
TSHR P16473 1/20 0.35
PTAFR P25105 1/20 0.35
KIF11 P52732 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 2/20 0.33
S1PR1 P21453 1/20 0.33
DGAT1 O75907 1/20 0.33
MAPT P10636 1/20 0.33
PARP1 P09874 1/20 0.33
NR1H4 Q96RI1 1/20 0.32
HTR1D P28221 1/20 0.32
ADRA1A P35348 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
ASIC1 P78348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29594761 1.00 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
Lithium SCHEMBL30438304 0.98 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL29040664 0.98 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL28148566 0.98 BRD4 (0.36) BRD4CREBBPTSHRPTAFRKIF11
Hydrochloric Acid SCHEMBL27911650 0.97 KIF11 (0.36) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL27911649 0.94 BRD4 (0.34) BRD4CREBBPTSHRPTAFRKIF11
SCHEMBL26606289 0.88 NR1H2 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL29594786 0.86 RXRB (0.36) PTAFRKIF11NPC1RAB9AALDH1A1
SCHEMBL6031753 0.86 RXRB (0.36) PTAFRKIF11NPC1RAB9AALDH1A1
SCHEMBL6150740 0.84 RXRB (0.35) PTAFRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606574-B2 Transition metal compound, method for preparing the same, and catalyst composition comprising the same LG CHEM, LTD. (KR) 2026-04-21 US disclosed
US-12384860-B2 Hybrid supported metallocene catalyst and process for preparing polyethylene copolymer using the same LG CHEM, LTD. (KR) 2025-08-12 US disclosed
US-12358938-B2 Transition metal compound and method of preparing polypropylene using the same LG CHEM, LTD. (KR) 2025-07-15 US disclosed
US-12139566-B2 Supported catalyst for propylene polymerization and method for producing polypropylene resin using same LOTTE CHEMICAL CORPORATION (KR) 2024-11-12 US disclosed
EP-3696184-B1 POLYOLEFIN CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING SAME LOTTE CHEMICAL CORP (KR) 2024-10-02 EP disclosed
US-12098158-B2 Transition metal compound, catalyst composition and method for preparing polypropylene using the same LG CHEM, LTD. (KR) 2024-09-24 US disclosed
EP-3744741-B1 PROPYLENE COPOLYMER RESIN COMPOSITION AND PREPARATION METHOD THEREFOR LG CHEMICAL LTD (KR) 2024-06-12 EP disclosed
US-20240124498-A1 TRANSITION METAL COMPOUND, METHOD FOR PREPARING THE SAME, AND CATALYST COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2024-04-18 US disclosed
US-20240109923-A1 TRANSITION METAL COMPOUND AND CATALYST COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2024-04-04 US disclosed
EP-3441407-B1 PROPYLENE-DIENE COPOLYMER RESIN HAVING EXCELLENT MELT TENSION LOTTE CHEMICAL CORP (KR) 2024-04-03 EP disclosed
EP-1397371-A1 METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS Basell Polyolefine GmbH (DE) 2004-03-17 EP disclosed
US-20040023940-A1 Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins EQUISTAR CHEMICALS, LP 2004-02-05 US disclosed
US-6627764-B1 Titanium, hafnium or zirconium indenyl halide complexes; coordination catalysts BASELL POLYOLEFINE GMBH (DE) 2003-09-30 US disclosed
US-20030149199-A1 Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins BASELL POLYPROPYLEN GMBH (DE) 2003-08-07 US disclosed
CN-1433435-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2003-07-30 CN disclosed
WO-2003045964-A1 METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS BASELL POLYOLEFINE GMBH (DE) 2003-06-05 WO disclosed
WO-2003000706-A1 METALLOCENES, USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS BASELL POLYOLEFINE GMBH (DE) 2003-01-03 WO disclosed
EP-1250365-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS Basell Polypropylen GmbH (DE) 2002-10-23 EP disclosed
US-6469114-B1 TO AVOID DEPOSIT FORMATION IN THE REACTOR, SUPPORTED CATALYST SYSTEMS IN WHICH THE METALLOCENE AND/OR THE ALUMINUM COMPOUNDS SERVING AS COCATALYST ARE FIXED ON AN INORGANIC SUPPORT MATERIAL HAVE BEEN PROPOSED BASELL POLYOLEFINS GMBH (DE) 2002-10-22 US disclosed
WO-2001048034-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12098158-B2 Transition metal compound, catalyst composition and method for preparing polypropylene using the same PMS2, POP1, MUS81 BRD4 4429/4885CREBBP 4101/4885TSHR 3875/4885
US-20240124498-A1 TRANSITION METAL COMPOUND, METHOD FOR PREPARING THE SAME, AND CATALYST COMPOSITION COMPRISING THE SAME UROD, SETD1B, SETD1A BRD4 2330/4885CREBBP 817/4885TSHR 4713/4885
US-12358938-B2 Transition metal compound and method of preparing polypropylene using the same PMS2, MUS81, PMM2 BRD4 3640/4885CREBBP 4059/4885TSHR 3740/4885
US-20030149199-A1 Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins PORCN, PGR, PPOX BRD4 1223/4885CREBBP 2360/4885TSHR 3596/4885
US-12139566-B2 Supported catalyst for propylene polymerization and method for producing polypropylene resin using same PPOX, POP1, PPIA BRD4 3610/4885CREBBP 2775/4885TSHR 3920/4885
US-20040023940-A1 Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins SOAT2, NOTUM, SOAT1 BRD4 1062/4885CREBBP 3466/4885TSHR 4832/4885
US-12606574-B2 Transition metal compound, method for preparing the same, and catalyst composition comprising the same ZRANB2, ZYX, ZKSCAN2 BRD4 3745/4885CREBBP 2017/4885TSHR 3955/4885
US-20240109923-A1 TRANSITION METAL COMPOUND AND CATALYST COMPOSITION COMPRISING THE SAME PCNA, EMG1, TAF1 BRD4 2498/4885CREBBP 2863/4885TSHR 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.