Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20641693 | 0.80 | TLR8 (0.44) | HRH4HRH3LMNABACE1 | |
| SCHEMBL6042497 | 0.78 | HRH4 (0.49) | HRH4HRH3TDP1L3MBTL1LMNA | |
| SCHEMBL20641735 | 0.77 | TLR8 (0.45) | HRH4HRH3TDP1L3MBTL1LMNA | |
| SCHEMBL30437918 | 0.77 | ALOX5AP (0.41) | HRH4HRH3CYSLTR1L3MBTL1LMNA | |
| SCHEMBL20641709 | 0.76 | TLR8 (0.44) | TDP1L3MBTL1LMNA | |
| SCHEMBL20641726 | 0.74 | ALK (0.44) | HRH4HRH3TDP1L3MBTL1LMNA | |
| SCHEMBL4004770 | 0.74 | L3MBTL1 (0.58) | HRH4HRH3TDP1L3MBTL1TSHR | |
| SCHEMBL23469024 | 0.72 | BACE1 (0.46) | CYSLTR1L3MBTL1LMNABACE1CYSLTR2 | |
| SCHEMBL2658064 | 0.71 | TSHR (0.54) | HRH4HRH3TDP1L3MBTL1MAOB | |
| SCHEMBL8192767 | 0.71 | HRH3 (0.47) | HRH4HRH3TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793060-B | NLRP3 modulators | 先天肿瘤免疫公司 | 2023-06-06 | — | — | CN | disclosed |