Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.33 |
| ▸ | FEN1 | P39748 | 5/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701645 | 1.00 | TGFBR1 (0.38) | TGFBR1PDPK1MAPK1TNIKALOX5AP | |
| SCHEMBL31529538 | 0.90 | TEAD1 (0.34) | PIK3CD | |
| SCHEMBL25703862 | 0.90 | SCN1A (0.35) | ALOX5APFEN1PIK3CDSCN1ASCN5A | |
| SCHEMBL30438685 | 0.90 | SCN1A (0.35) | ALOX5APFEN1PIK3CDSCN1ASCN5A | |
| SCHEMBL25702513 | 0.82 | MOGAT2 (0.32) | ALOX5APFEN1MOGAT2HDAC6CTSL | |
| SCHEMBL30438919 | 0.82 | MOGAT2 (0.32) | ALOX5APFEN1MOGAT2HDAC6CTSL | |
| SCHEMBL25437180 | 0.78 | PIK3CA (0.40) | ALOX5APFEN1MOGAT2SCN1ASCN5A | |
| SCHEMBL31529481 | 0.78 | PIK3CA (0.40) | ALOX5APFEN1MOGAT2SCN1ASCN5A | |
| SCHEMBL30438528 | 0.78 | ALOX5AP (0.38) | MAPK1ALOX5APFEN1MOGAT2CTSL | |
| SCHEMBL30438715 | 0.78 | ALOX5AP (0.33) | ALOX5APFEN1MOGAT2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436955-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | Lario Therapeutics Limited (GB) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |