Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 7/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20952090 | 0.85 | RET (0.41) | RETSTAT3STAT1DRD2DRD4 | |
| SCHEMBL24638845 | 0.70 | RET (0.42) | RETSMYD3NPC1RAB9ATSHR | |
| SCHEMBL19900076 | 0.70 | STAT1 (0.50) | RETSTAT3STAT1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL30437434 | 0.69 | STAT1 (0.49) | RETSTAT3STAT1DRD2DRD4 | |
| Iodide SCHEMBL29388459 | 0.69 | STAT1 (0.49) | RETSTAT3STAT1DRD2DRD4 | |
| SCHEMBL30437727 | 0.66 | STAT1 (0.51) | RETSTAT3STAT1DRD2DRD4 | |
| SCHEMBL17301340 | 0.65 | RAB9A (0.50) | RETSTAT3STAT1DRD2DRD4 | |
| SCHEMBL11836452 | 0.63 | NPC1 (0.45) | RETDRD2DRD4DRD3NPC1 | |
| SCHEMBL30605718 | 0.63 | STAT3 (0.52) | RETSTAT3STAT1DRD2DRD4 | |
| SCHEMBL21179066 | 0.62 | RET (0.43) | RETSTAT3STAT1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | disclosed |