Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287309 | 0.82 | ALDH1A1 (0.50) | KMT2ACYP1A2CYP2C19GAALMNA | |
| SCHEMBL6339999 | 0.73 | ALDH1A1 (0.49) | KMT2ALMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25247101 | 0.71 | CYP1A2 (0.50) | KMT2ACYP1A2CYP2C19GAALMNA | |
| Benzyl Bromide SCHEMBL7350277 | 0.69 | ALDH1A1 (0.45) | KMT2ALMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL16832228 | 0.68 | GAA (0.69) | CYP1A2CYP2C19GAALMNAALDH1A1 | |
| SCHEMBL28505124 | 0.68 | PPARG (0.52) | KMT2ALMNAALDH1A1MAPTNPC1 | |
| SCHEMBL14124978 | 0.66 | MAPK1 (0.57) | KMT2AGAALMNAALDH1A1MEN1 | |
| SCHEMBL6202269 | 0.66 | SMN1; SMN2 (0.44) | KMT2ACYP1A2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15937249 | 0.66 | KMT2A (0.52) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL9912563 | 0.65 | MAPK1 (0.47) | KMT2ALMNAALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099648-A1 | PYRAOLO- AND TRIAZOLO-AZINONE COMPOUNDS AND THEIR USES | ASTRAZENECA AB (SE) | 2023-06-08 | — | — | WO | disclosed |