SCHEMBL30438963

SCHEMBL30438963

CC(C)ON(C(=O)Oc1ccccc1)N(OC(C)C)C(=O)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
NPY5R Q15761 1/20 0.47
KMT2A Q03164 5/20 0.45
ALDH1A1 P00352 4/20 0.45
PKM P14618 1/20 0.45
MEN1 O00255 4/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 5/20 0.44
NPSR1 Q6W5P4 2/20 0.42
NPC1 O15118 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ELANE P08246 1/20 0.41
ACHE P22303 1/20 0.41
PTGES O14684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858698 0.84 L3MBTL1 (0.50) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL30439094 0.79 TDP1 (0.57) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL29025476 0.77 ATM (0.55) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL3475218 0.76 NPY5R (0.59) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL30438766 0.74 TDP1 (0.52) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL30439056 0.74 L3MBTL1 (0.52) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL27451415 0.74 L3MBTL1 (0.52) ATML3MBTL1TDP1NPY5RKMT2A
Phenyl Dimethylcarbamate SCHEMBL491227 0.74 RAB9A (0.78) ATML3MBTL1TDP1KMT2AALDH1A1
SCHEMBL11212298 0.74 TDP1 (0.61) ATML3MBTL1TDP1NPY5RKMT2A
SCHEMBL4437071 0.74 TDP1 (0.61) ATML3MBTL1TDP1NPY5RKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375607-A Hydrazine compound and preparation method and application thereof 南京信息工程大学 2023-07-04 CN disclosed