Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPC6 | Q9Y210 | 12/20 | 0.45 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045708 | 1.00 | MEN1 (0.45) | MEN1KMT2ATRPC6MAPK7MCHR1 | |
| SCHEMBL30439314 | 0.87 | TRPC6 (0.56) | TRPC6 | |
| SCHEMBL21045625 | 0.87 | TRPC6 (0.56) | TRPC6 | |
| SCHEMBL21045700 | 0.86 | TRPC6 (0.54) | TRPC6 | |
| SCHEMBL30439705 | 0.86 | TRPC6 (0.54) | TRPC6 | |
| SCHEMBL21045670 | 0.85 | TRPC6 (0.56) | TRPC6 | |
| SCHEMBL21085409 | 0.84 | TRPC6 (0.47) | TRPC6 | |
| SCHEMBL21045627 | 0.84 | TTR (0.57) | TRPC6 | |
| SCHEMBL21045884 | 0.83 | TRPC6 (0.54) | TRPC6 | |
| SCHEMBL21045905 | 0.82 | TRPC6 (0.56) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527078-B | Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors | 勃林格殷格翰国际公司 | 2023-06-02 | — | — | CN | disclosed |