Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SPR | P35270 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768128 | 1.00 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL20768129 | 1.00 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19492653 | 0.88 | PDE2A (0.57) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL20768137 | 0.88 | PDE2A (0.57) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL20768127 | 0.85 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19463255 | 0.85 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19492490 | 0.83 | TAS1R3 (0.54) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19492489 | 0.83 | TAS1R3 (0.54) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19463266 | 0.80 | TAS1R3 (0.52) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19463267 | 0.80 | TAS1R3 (0.52) | PDE2AALDH1A1SPRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |