Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SPR | P35270 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439617 | 1.00 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL20768128 | 1.00 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19492653 | 0.88 | PDE2A (0.57) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL20768137 | 0.88 | PDE2A (0.57) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL20768127 | 0.85 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19463255 | 0.85 | PDE2A (0.55) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19492490 | 0.83 | TAS1R3 (0.54) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19492489 | 0.83 | TAS1R3 (0.54) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19463266 | 0.80 | TAS1R3 (0.52) | PDE2AALDH1A1SPRTAS1R3TAS1R1 | |
| SCHEMBL19463267 | 0.80 | TAS1R3 (0.52) | PDE2AALDH1A1SPRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-11001590-B2 | Pyrazolopyrimidine derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| US-10934301-B2 | Pyrazolopyrimidine derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| US-20200299299-A1 | NEW PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| US-20200239482-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-07-30 | — | — | US | disclosed |
| US-10604525-B2 | Pyrazolopyrimidine derivatives | BAYAL ANIMAL HEALTH GMBH (DE) | 2020-03-31 | — | — | US | disclosed |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604525-B2 | Pyrazolopyrimidine derivatives | P2RX5, RECQL, P2RX1 | PDE2A 816/4885ALDH1A1 1297/4885SPR 1441/4885 |
| US-11001590-B2 | Pyrazolopyrimidine derivatives | P2RX5, RECQL, P2RX1 | PDE2A 785/4885ALDH1A1 1228/4885SPR 1409/4885 |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | P2RX5, RECQL, P2RX1 | PDE2A 816/4885ALDH1A1 1297/4885SPR 1441/4885 |
| US-20200239482-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | P2RX5, RECQL, P2RX1 | PDE2A 785/4885ALDH1A1 1228/4885SPR 1409/4885 |
| US-10934301-B2 | Pyrazolopyrimidine derivatives | P2RX5, RECQL, P2RX1 | PDE2A 785/4885ALDH1A1 1228/4885SPR 1409/4885 |
| US-20200299299-A1 | NEW PYRAZOLOPYRIMIDINE DERIVATIVES | P2RX5, RECQL, P2RX1 | PDE2A 684/4885ALDH1A1 1241/4885SPR 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.