Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 6/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439004 | 0.95 | MME (0.45) | MMENPY1RNPY2RNPY4RALDH1A1 | |
| SCHEMBL29775576 | 0.93 | ALDH1A1 (0.47) | MMENPY1RNPY2RNPY4RALDH1A1 | |
| SCHEMBL29775621 | 0.93 | ALDH1A1 (0.47) | MMENPY1RNPY2RNPY4RALDH1A1 | |
| SCHEMBL30438951 | 0.93 | BACE1 (0.47) | MMENPY1RNPY2RNPY4RBACE1 | |
| SCHEMBL30439183 | 0.92 | MME (0.42) | MMENPY1RNPY2RNPY4RBACE1 | |
| SCHEMBL29893601 | 0.92 | ALDH1A1 (0.49) | MMENPY1RNPY2RNPY4RALDH1A1 | |
| SCHEMBL29775548 | 0.90 | ALDH1A1 (0.50) | MMENPY1RNPY2RNPY4RALDH1A1 | |
| SCHEMBL30439402 | 0.90 | TASP1 (0.49) | — | |
| SCHEMBL29775555 | 0.88 | BACE1 (0.46) | MMENPY1RNPY2RNPY4RBACE1 | |
| SCHEMBL29354569 | 0.88 | MME (0.48) | MMENPY1RNPY2RNPY4RNMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556769-B1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | INST MED BIOTECHNOLOGY CAMS (CN) | 2023-06-14 | — | — | EP | disclosed |