Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416904 | 1.00 | FOLH1 (0.49) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL28416898 | 1.00 | FOLH1 (0.49) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL22127992 | 0.94 | CA2 (0.46) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL22127827 | 0.94 | CA2 (0.46) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL22127991 | 0.94 | CA2 (0.46) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL22127833 | 0.94 | CA2 (0.46) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL30440174 | 0.94 | CA2 (0.46) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL22127830 | 0.94 | CA2 (0.46) | FOLH1CPB1CPB2PTGER4ELANE | |
| SCHEMBL22127969 | 0.90 | FOLH1 (0.56) | FOLH1CPB1CPB2PTGER4HTR2C | |
| SCHEMBL22127970 | 0.90 | FOLH1 (0.56) | FOLH1CPB1CPB2PTGER4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | FOLH1 1463/4885CPB1 4443/4885CPB2 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.