Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | GRM5 | P41594 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190227 | 1.00 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL13841479 | 0.84 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL8240316 | 0.84 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL20095383 | 0.84 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL9885823 | 0.83 | ALDH1A1 (0.67) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL10665125 | 0.83 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL2578961 | 0.81 | ALDH1A1 (0.71) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL13026590 | 0.80 | SMN1; SMN2 (0.81) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL31725239 | 0.80 | RAB9A (0.78) | RAB9ANPC1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL14353530 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2GRM5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438167-A | Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof | 美迪福伦DBT有限公司 | 2023-07-14 | — | — | CN | disclosed |