Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.60 |
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | RXRB | P28702 | 2/20 | 0.56 |
| ▸ | RXRG | P48443 | 2/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314656 | 1.00 | CREBBP (0.60) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL30440212 | 0.88 | THRA (0.56) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL17386686 | 0.88 | THRA (0.56) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL312486 | 0.88 | CREBBP (0.56) | CREBBPRXRARXRBRXRGCYP1A2 | |
| SCHEMBL313614 | 0.88 | CYP2C9 (0.48) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL1402196 | 0.88 | TSHR (0.60) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL16960225 | 0.87 | RXRA (0.51) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL17407193 | 0.87 | THRA (0.61) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL17339621 | 0.86 | RXRA (0.54) | CREBBPRXRARXRBRXRGTHRA | |
| SCHEMBL10323654 | 0.85 | RXRA (0.45) | CREBBPRXRARXRBRXRGTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845490-B | 2-acylaminothiazole derivative or salt thereof | 旭飞药业股份有限公司 | 2023-03-28 | — | — | CN | disclosed |