Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25276481 | 1.00 | MGAM (0.46) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL25731715 | 0.82 | ACHE (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27316377 | 0.78 | USP7 (0.44) | SMN1; SMN2KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL24655966 | 0.78 | KMT2A (0.41) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL14125145 | 0.76 | GAA (0.56) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL12844824 | 0.76 | KMT2A (0.50) | GAAKMT2ATSHRALDH1A1LMNA | |
| SCHEMBL29685392 | 0.76 | KMT2A (0.50) | GAAKMT2ATSHRALDH1A1LMNA | |
| SCHEMBL21818874 | 0.76 | LMNA (0.54) | MAPK1TSHRRAB9ALMNAHTT | |
| SCHEMBL14401081 | 0.75 | TDP1 (0.50) | SMN1; SMN2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL16911735 | 0.74 | MAPT (0.52) | GAASMN1; SMN2KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4444312-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |