Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.62 |
| ▸ | EGFR | P00533 | 3/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25261399 | 1.00 | CSF1R (0.62) | CSF1REGFRPRMT5HPGDSKIT | |
| SCHEMBL3536147 | 0.76 | EGFR (0.58) | CSF1REGFRHPGDSMAPK1JAK2 | |
| SCHEMBL25638057 | 0.76 | HPGDS (0.56) | CSF1REGFRHPGDSIRAK4JAK2 | |
| SCHEMBL30441144 | 0.75 | EGFR (0.45) | CSF1REGFRHPGDSIRAK4CDC7 | |
| SCHEMBL10668360 | 0.75 | EGFR (0.45) | CSF1REGFRHPGDSIRAK4CDC7 | |
| SCHEMBL13737573 | 0.72 | KIT (0.61) | CSF1REGFRPRMT5KITMAP4K4 | |
| SCHEMBL10668363 | 0.72 | LMNA (0.52) | CSF1REGFRHPGDSIRAK4CDC7 | |
| SCHEMBL3982349 | 0.71 | KIT (0.59) | CSF1REGFRKITCDC7BRAF | |
| SCHEMBL3982045 | 0.71 | KIT (0.59) | CSF1REGFRKITBRAFTNNI3K | |
| SCHEMBL3542880 | 0.71 | CSF1R (0.79) | CSF1REGFRPRMT5JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098699-A1 | COMPOUNDS AND THEIR USES AS CD38 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-06-08 | — | — | WO | claimed |
| WO-2023098699-A1 | COMPOUNDS AND THEIR USES AS CD38 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-06-08 | — | — | WO | disclosed |