Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578428 | 0.91 | PDE4B (0.45) | NOS1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL20331765 | 0.91 | PDE4B (0.45) | NOS1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL20331791 | 0.89 | PDE4B (0.35) | NOS1MEN1KMT2APDE4BPDE4A | |
| SCHEMBL29577481 | 0.89 | TTK (0.38) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL21240619 | 0.89 | TTK (0.38) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL21252148 | 0.88 | MEN1 (0.39) | NOS1MEN1KMT2APDE4BPDE4A | |
| SCHEMBL30046092 | 0.88 | TTK (0.36) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL20331784 | 0.88 | TTK (0.36) | PDE4BPDE4APDE4CPDE4DPDE11A | |
| SCHEMBL21240537 | 0.87 | NOS1 (0.36) | NOS1MEN1KMT2APDE4BPDE4A | |
| SCHEMBL29578158 | 0.87 | NOS1 (0.36) | NOS1MEN1KMT2APDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868058-B | FGFR inhibitor, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-06-13 | — | — | CN | disclosed |