Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 14/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 14/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 14/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 14/20 | 0.51 |
| ▸ | PRKAG3 | Q9UGI9 | 14/20 | 0.51 |
| ▸ | PRKAG2 | Q9UGJ0 | 14/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379535 | 1.00 | MAP2K4 (0.61) | MAP2K4GSK3BPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL570293 | 0.86 | PRKAG1 (0.55) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17423733 | 0.85 | MAP2K4 (0.52) | MAP2K4GSK3BPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL15540985 | 0.85 | MAP2K4 (0.52) | MAP2K4GSK3BPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4791992 | 0.81 | MAP2K4 (0.65) | MAP2K4GSK3BKDM4EMEN1LMNA | |
| SCHEMBL30609861 | 0.81 | MAP2K4 (0.65) | MAP2K4GSK3BKDM4EMEN1LMNA | |
| SCHEMBL17423779 | 0.81 | GSK3B (0.49) | MAP2K4GSK3BPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL12879075 | 0.81 | PRKAG1 (0.46) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL176936 | 0.81 | PRKAG1 (0.55) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL11170521 | 0.80 | ROCK1 (0.46) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023085785-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | 한국화학연구원 | 2023-05-19 | — | — | WO | disclosed |