Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533801 | 1.00 | HDAC1 (0.47) | HDAC1HDAC8HDAC6GSRALDH1A1 | |
| SCHEMBL3533797 | 1.00 | HDAC1 (0.47) | HDAC1HDAC8HDAC6GSRALDH1A1 | |
| SCHEMBL9274151 | 0.84 | PTPN1 (0.45) | ALDH1A1MEN1KMT2ALMNATRPA1 | |
| SCHEMBL9274152 | 0.84 | PTPN1 (0.45) | ALDH1A1MEN1KMT2ALMNATRPA1 | |
| SCHEMBL2355534 | 0.83 | PPP1R15A (0.43) | HDAC1ALDH1A1GRIK1GRIK2MAPT | |
| SCHEMBL15539237 | 0.83 | CHAT (0.44) | HDAC1HDAC8HDAC6GSRALDH1A1 | |
| SCHEMBL2355528 | 0.83 | PPP1R15A (0.43) | HDAC1ALDH1A1GRIK1GRIK2MAPT | |
| SCHEMBL5319574 | 0.83 | CHAT (0.44) | HDAC1HDAC8HDAC6GSRALDH1A1 | |
| SCHEMBL14691573 | 0.80 | GAA (0.33) | HDAC1HDAC8HDAC6GSRALDH1A1 | |
| SCHEMBL31500768 | 0.80 | ALDH1A1 (0.48) | HDAC1HDAC8HDAC6GSRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234798-A | Sulfamate derivative compounds for the treatment or alleviation of psychotic disorders | 生物药品解决方案有限公司 | 2023-06-06 | — | — | CN | disclosed |