Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274152 | 1.00 | PTPN1 (0.45) | PTPN1ALDH1A1CYP3A4RECQLNFE2L2 | |
| SCHEMBL229461 | 0.85 | TRPA1 (0.54) | ALDH1A1CYP3A4RECQLNFE2L2LMNA | |
| SCHEMBL13158791 | 0.85 | TRPA1 (0.54) | ALDH1A1CYP3A4RECQLNFE2L2LMNA | |
| SCHEMBL4630799 | 0.85 | TRPA1 (0.54) | ALDH1A1CYP3A4RECQLNFE2L2LMNA | |
| SCHEMBL30528037 | 0.85 | TRPA1 (0.54) | ALDH1A1CYP3A4RECQLNFE2L2LMNA | |
| SCHEMBL24075882 | 0.84 | PTPN1 (0.43) | PTPN1ALDH1A1CYP3A4RECQLTSHR | |
| SCHEMBL3533797 | 0.84 | HDAC1 (0.47) | ALDH1A1NFE2L2MEN1LMNAKMT2A | |
| SCHEMBL4090323 | 0.84 | NFE2L2 (0.62) | NFE2L2NFKB1CYP1A2 | |
| SCHEMBL320615 | 0.84 | NFE2L2 (0.62) | NFE2L2NFKB1CYP1A2 | |
| SCHEMBL3815276 | 0.84 | HSD11B1 (0.53) | PTPN1ALDH1A1CYP3A4RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399676-A | DNA sequence identification | GILEAD SCIENCES (US) | 1995-03-21 | — | — | US | claimed |
| US-20140107373-A1 | Polyvalent Vinyl Aromatic Compound and Method for Producing Same | Tokyo Instutute of Technology (JP) | 2014-04-17 | — | — | US | disclosed |
| US-20140107373-A1 | Polyvalent Vinyl Aromatic Compound and Method for Producing Same | Tokyo Instutute of Technology (JP) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107373-A1 | Polyvalent Vinyl Aromatic Compound and Method for Producing Same | PAH, AVPR1A, VDAC1 | PTPN1 2365/4885ALDH1A1 1783/4885CYP3A4 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.