Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445543 | 0.76 | ALDH1A1 (0.33) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL6969595 | 0.75 | DDB1 (0.38) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL23795442 | 0.73 | DDB1 (0.36) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL2277430 | 0.71 | NR1H2 (0.44) | CHRM2CHRM1CHRM3CTSKALDH1A1 | |
| SCHEMBL31506576 | 0.71 | CHRM2 (0.36) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL19915056 | 0.69 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL29102381 | 0.69 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL220833 | 0.69 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL622600 | 0.69 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL26143938 | 0.69 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111107848-B | Pharmaceutical composition containing amide derivatives, and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-05-23 | — | — | CN | disclosed |