Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14790378 | 0.87 | NR1H2 (0.37) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL6969595 | 0.75 | DDB1 (0.38) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL15348412 | 0.75 | ALDH1A1 (0.38) | KDM4EMAPTHPGD | |
| SCHEMBL15348414 | 0.75 | ALDH1A1 (0.38) | KDM4EMAPTHPGD | |
| SCHEMBL30444166 | 0.73 | DDB1 (0.36) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL13864152 | 0.73 | CHRM2 (0.40) | CHRM2CHRM1CHRM3KDM4EMAPT | |
| SCHEMBL18901858 | 0.72 | FAAH (0.36) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL622600 | 0.72 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL220833 | 0.72 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 | |
| SCHEMBL19915056 | 0.72 | CHRM2 (0.46) | DDB1CRBNCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875151-A1 | ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO [4.3.1] DECANE DERIVATES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Technische Universität Darmstadt (DE) | 2021-09-08 | — | — | EP | disclosed |