Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | PTGIR | P43119 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444153 | 0.86 | NR1H4 (0.55) | NR1H4PTGIRMGLLAPEX1RAB9A | |
| SCHEMBL17346623 | 0.84 | PTGIR (0.81) | PTGIRMGLLBCHEMAOBACHE | |
| SCHEMBL4966292 | 0.83 | NPC1 (0.64) | PTGIRMGLLRAB9ANPC1HPGD | |
| SCHEMBL4964970 | 0.82 | MGLL (0.63) | PTGIRMGLLBCHEMAOBACHE | |
| SCHEMBL17344408 | 0.81 | MGLL (0.73) | PTGIRMGLLBCHEMAOBACHE | |
| SCHEMBL10658594 | 0.80 | LMNA (0.68) | NR1H4RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL118921 | 0.79 | EPHX2 (0.73) | NR1H4RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL30089345 | 0.79 | EPHX2 (0.73) | NR1H4RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL29400630 | 0.79 | EPHX2 (0.73) | NR1H4RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL6516120 | 0.78 | PTGIR (0.72) | PTGIRMGLLBCHEMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | claimed |
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |