Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629468 | 1.00 | AXL (0.43) | AXLHTR2AHTR2CTLR8ADORA3 | |
| SCHEMBL23629462 | 0.70 | AXL (0.42) | AXLHTR2AHTR2CADORA3ADORA1 | |
| SCHEMBL14995475 | 0.70 | AXL (0.51) | AXLHTR2AHTR2CTLR8ADORA3 | |
| SCHEMBL2433235 | 0.65 | AXL (0.49) | AXLHTR2AHTR2CADORA3ADORA1 | |
| SCHEMBL3396139 | 0.65 | CA2 (0.43) | HTR2AHTR2CALDH1A1AMY1AMAPT | |
| SCHEMBL680200 | 0.64 | AXL (0.87) | AXLHTR2AHTR2CTLR8ALDH1A1 | |
| SCHEMBL25204558 | 0.64 | AXL (0.44) | AXLHTR2AHTR2CTLR8ADORA3 | |
| SCHEMBL3560175 | 0.62 | AXL (0.73) | AXLTLR8ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24032943 | 0.62 | AXL (0.49) | AXLHTR2AHTR2CADORA3ADORA1 | |
| SCHEMBL5483794 | 0.61 | HPGD (0.62) | AXLHTR2AHTR2CALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739691-B | TRK inhibitors as anticancer agents | 泰励生物科技（上海）有限公司 | 2023-05-23 | — | — | CN | disclosed |