SCHEMBL30444565

SCHEMBL30444565

CCCCCCCCC(=O)NCCc1cccnc1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.67
MAPT P10636 2/20 0.64
LMNA P02545 1/20 0.60
POLB P06746 1/20 0.60
EPHX2 P34913 2/20 0.59
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CYP3A4 P08684 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TRPV1 Q8NER1 1/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
TBXAS1 P24557 2/20 0.55
PTAFR P25105 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186612 1.00 FAAH (0.67) FAAHMAPTLMNAPOLBEPHX2
SCHEMBL8422210 0.86 HPGD (0.63) FAAHMAPTTDP1L3MBTL1CYP3A4
SCHEMBL11085067 0.86 MAPT (0.86) FAAHMAPTLMNAPOLBEPHX2
SCHEMBL7761440 0.86 MAPT (0.86) FAAHMAPTLMNAPOLBEPHX2
SCHEMBL18381301 0.86 MAPT (0.59) FAAHMAPTLMNACYP3A4MEN1
SCHEMBL16610103 0.86 CYP3A4 (0.61) MAPTLMNACYP3A4MEN1KMT2A
SCHEMBL25407680 0.85 FAAH (0.51) FAAHMAPTLMNAPOLBEPHX2
SCHEMBL25407687 0.85 FAAH (0.51) FAAHMAPTLMNAPOLBEPHX2
SCHEMBL18381201 0.84 CYP3A4 (0.67) MAPTLMNACYP3A4MEN1KMT2A
SCHEMBL16353740 0.84 TBXAS1 (0.67) MAPTLMNACYP3A4TBXAS1PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230094176-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS CERENO SCIENT AB (SE) 2023-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230094176-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS HDAC3, HDAC2, HDAC1 FAAH 235/4885MAPT 735/4885LMNA 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.