Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.61 |
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445391 | 1.00 | EPHX2 (0.61) | EPHX2FAAHTRPV1HDAC1HDAC2 | |
| SCHEMBL531059 | 0.83 | HPGD (0.61) | TRPV1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL12505085 | 0.81 | TRPV1 (0.53) | TRPV1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL30444576 | 0.80 | HDAC1 (0.81) | TRPV1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL27403714 | 0.79 | EPHX2 (0.67) | EPHX2FAAHTRPV1HDAC1HDAC2 | |
| SCHEMBL17954341 | 0.79 | TRPV1 (0.51) | TRPV1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19864372 | 0.79 | ATG4B (0.53) | FAAHHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5471650 | 0.77 | EPHX2 (1.00) | EPHX2FAAHTRPV1CNR1CNR2 | |
| SCHEMBL16714726 | 0.77 | EPHX2 (1.00) | EPHX2FAAHTRPV1CNR1CNR2 | |
| Nonanoic Acid Benzylamide SCHEMBL3280214 | 0.77 | EPHX2 (1.00) | EPHX2FAAHTRPV1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENT AB (SE) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC2, HDAC1 | EPHX2 3208/4885FAAH 235/4885TRPV1 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.