Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12672516 | 0.87 | NPC1 (0.74) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL12658954 | 0.87 | NPC1 (0.74) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL7203505 | 0.87 | RAB9A (1.00) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL1232359 | 0.86 | RAB9A (0.72) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL28931481 | 0.85 | RAB9A (0.91) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL4162609 | 0.84 | RAB9A (0.62) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL1193340 | 0.84 | RAB9A (0.74) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL15975495 | 0.83 | EPHX1 (0.79) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL9291930 | 0.83 | MEN1 (1.00) | RAB9ASMN1; SMN2LMNANPC1HDAC1 | |
| SCHEMBL30444774 | 0.82 | HDAC1 (0.71) | RAB9ASMN1; SMN2LMNANPC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENT AB (SE) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC2, HDAC1 | RAB9A 3925/4885SMN1; SMN2 3053/4885LMNA 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.