Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.79 |
| ▸ | SMO | Q99835 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 10/20 | 0.79 |
| ▸ | TP53 | P04637 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | COMT | P21964 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211422 | 1.00 | MAPK14 (0.79) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL3766274 | 0.89 | MAPK14 (1.00) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL14615278 | 0.88 | MAPT (1.00) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL3685018 | 0.84 | SMO (0.80) | MAPK14SMOMAPT | |
| SCHEMBL3687967 | 0.81 | SMO (0.87) | MAPK14SMOMAPT | |
| SCHEMBL14615292 | 0.81 | MAPT (0.69) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL25232982 | 0.81 | MAPT (0.63) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL30442877 | 0.81 | MAPT (0.63) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL14615293 | 0.81 | MAPT (0.72) | MAPK14SMOMAPTTP53SMN1; SMN2 | |
| SCHEMBL25208976 | 0.80 | MAPT (0.68) | MAPK14SMOMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | MAPK14 2633/4885SMO 4353/4885MAPT 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.