Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | SMO | Q99835 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25232982 | 1.00 | MAPT (0.63) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL25200815 | 0.87 | COMT (0.63) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL30443231 | 0.87 | COMT (0.63) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL14615274 | 0.85 | MAPT (0.80) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL12848892 | 0.83 | PDE4A (0.57) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL25656244 | 0.82 | COMT (0.64) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL14615276 | 0.81 | MAPT (0.76) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL25211422 | 0.81 | MAPK14 (0.79) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL30445799 | 0.81 | MAPK14 (0.79) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL25208344 | 0.81 | MAPT (0.62) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153172-B1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NAT RECH SCIENT (FR) | 2024-11-27 | — | — | EP | claimed |
| EP-4153172-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | Centre National de la Recherche Scientifique (FR) | 2023-03-29 | — | — | EP | claimed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
| EP-4153172-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | Centre National de la Recherche Scientifique (FR) | 2023-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | MAPT 781/4885SMN1; SMN2 4842/4885TP53 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.