Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PON1 | P27169 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591570 | 1.00 | HPGD (0.47) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL26476663 | 0.81 | ALDH1A1 (0.45) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12663610 | 0.81 | KDM4E (0.50) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15676021 | 0.76 | KMT2A (0.61) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8406816 | 0.71 | LMNA (0.42) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL28471407 | 0.71 | CSNK2A2 (0.50) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL14070840 | 0.71 | PON1 (0.50) | ALDH1A1MEN1KMT2APON1MCL1 | |
| SCHEMBL954406 | 0.70 | CYP1A2 (0.38) | SMN1; SMN2MCL1NQO1KDM4EMAOA | |
| SCHEMBL20793964 | 0.70 | SMN1; SMN2 (0.53) | HPGDALDH1A1PON1SMN1; SMN2MCL1 | |
| SCHEMBL21591455 | 0.68 | PON1 (0.55) | HPGDALDH1A1MEN1KMT2APON1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120313-B | Pyridoimidazole nitrogen fused ring compound and preparation method and application thereof | 遵义医科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-116120313-A | Pyridoimidazole nitrogen fused ring compound and preparation method and application thereof | 遵义医科大学 | 2023-05-16 | — | — | CN | disclosed |