Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206858 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL30446110 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL22206828 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL22206882 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL30446080 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL31074204 | 0.85 | PSEN1 (0.45) | TP53LMNAKMT2AMEN1PSEN1 | |
| SCHEMBL3192743 | 0.84 | ADRA2C (0.50) | TSHRHSD17B10TP53ADRA2CLMNA | |
| SCHEMBL31074209 | 0.84 | ADRA2C (0.50) | TSHRHSD17B10TP53ADRA2CLMNA | |
| SCHEMBL20943342 | 0.82 | PSEN1 (0.43) | HSD17B10CYP3A4TDP1TP53ADRA2C | |
| SCHEMBL20943341 | 0.82 | PSEN1 (0.43) | HSD17B10CYP3A4TDP1TP53ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111434671-B | Liver-specific AMPK agonist and preparation method and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2023-07-11 | — | — | CN | disclosed |