Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 11/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HBB | P68871 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170756 | 0.93 | MAPT (0.37) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL2162138 | 0.85 | MAPT (0.35) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL28346195 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL7796649 | 0.84 | MAPT (0.38) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL11256547 | 0.82 | MAPT (0.37) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL10535947 | 0.77 | MAPT (0.36) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL3423479 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL16322074 | 0.76 | MAPT (0.40) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL7646733 | 0.76 | MAPT (0.40) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL4582755 | 0.75 | ALDH1A1 (0.37) | MAPTMEN1KMT2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227414-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227414-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | MAPT 4599/4885MEN1 3831/4885KMT2A 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.