Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582755 | 0.87 | ALDH1A1 (0.37) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL16322074 | 0.85 | MAPT (0.40) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7646733 | 0.85 | MAPT (0.40) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL30446337 | 0.84 | MAPT (0.39) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11170756 | 0.81 | MAPT (0.37) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11256547 | 0.81 | MAPT (0.37) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL1426467 | 0.80 | MEN1 (0.39) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL10853904 | 0.77 | MEN1 (0.44) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL28346195 | 0.76 | MAPT (0.41) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL31380893 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835233-B1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | NEN LIFE SCIENCE PROD INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-4163092-A | QUATERNIZED MONOMER, CROSS-LINKING AGENT | PLASTOMEDICAL SCIENCES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4058491-A | Cationic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-15 | — | — | US | disclosed |