SCHEMBL30446674

CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CN)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21

nearest known ligand 0.56

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PRMT6	Q96LA8	1/20	0.54

▸	P2RY12	Q9H244	5/20	0.48

▸	BMPR1B	O00238	1/20	0.45

▸	ADORA1	P30542	1/20	0.44

▸	P2RX3	P56373	1/20	0.44

▸	P2RX4	Q99571	1/20	0.44

▸	P2RX2	Q9UBL9	1/20	0.44

▸	P2RY2	P41231	1/20	0.44

▸	P2RY1	P47900	1/20	0.44

▸	P2RY6	Q15077	1/20	0.44

▸	DNPH1	O43598	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22206829	1.00	PRMT6 (0.54)	PRMT6P2RY12BMPR1BADORA1P2RX3
SCHEMBL7032101	0.93	PRMT6 (0.51)	PRMT6P2RY12ADORA1
SCHEMBL30446733	0.93	PRMT6 (0.51)	PRMT6P2RY12ADORA1
SCHEMBL8937133	0.93	PRMT6 (0.51)	PRMT6P2RY12ADORA1
SCHEMBL22206844	0.91	PRMT6 (0.50)	PRMT6P2RY12BMPR1BADORA1P2RX3
SCHEMBL29479254	0.89	PRMT6 (0.52)	PRMT6P2RY12ADORA1P2RX3P2RX4
SCHEMBL26653470	0.89	PRMT6 (0.49)	PRMT6P2RY12ADORA1
SCHEMBL19128447	0.89	PRMT6 (0.51)	PRMT6P2RY12ADORA1
SCHEMBL19128052	0.89	PRMT6 (0.51)	PRMT6P2RY12ADORA1
SCHEMBL13020575	0.89	MEN1 (0.50)	PRMT6P2RY12ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111434671-B	Liver-specific AMPK agonist and preparation method and application thereof	凯思凯迪（上海）医药科技有限公司	2023-07-11	—	—	CN	disclosed