Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | HPGDS | O60760 | 6/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20023727 | 1.00 | PDGFRB (0.41) | PDGFRBPDGFRAHPGDSMGAMMAP4K4 | |
| SCHEMBL19021348 | 0.84 | HPGDS (0.34) | PDGFRBPDGFRAHPGDSMGAMMAP4K4 | |
| SCHEMBL1645063 | 0.84 | KIF11 (0.46) | HPGDSMAP4K4CSNK1G2CLK4MKNK2 | |
| SCHEMBL7086111 | 0.84 | MGAM (0.56) | PDGFRBPDGFRAHPGDSMGAMALDH1A1 | |
| SCHEMBL7081027 | 0.82 | HPGDS (0.53) | PDGFRBPDGFRAHPGDSMGAMCYP11B2 | |
| SCHEMBL7227312 | 0.78 | MAOB (0.54) | PDGFRBPDGFRAMAOBALDH1A1 | |
| SCHEMBL19021406 | 0.78 | HTT (0.41) | HPGDSALDH1A1HPGD | |
| SCHEMBL19021372 | 0.78 | HPGDS (0.36) | HPGDSALDH1A1HPGD | |
| SCHEMBL20023728 | 0.77 | HPGDS (0.39) | PDGFRBPDGFRAHPGDSALDH1A1F2 | |
| SCHEMBL15447957 | 0.74 | MGAM (0.41) | HPGDSMGAMMAP4K4CSNK1G2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854693-A | P2X 3 And/or P2X 2/3 Compounds and methods | 阿沙纳生物科学公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-109996546-B | P2X 3 And/or P2X 2/3 Compounds and methods | 阿沙纳生物科学公司 | 2023-06-27 | — | — | CN | disclosed |