Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 2/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485825 | 0.83 | AVPR1A (0.43) | AVPR1ACCNCCDK8HASPINCDK19 | |
| Hydrochloric Acid SCHEMBL1003364 | 0.82 | AVPR1A (0.43) | AVPR1ACCNCCDK8HASPINCDK19 | |
| SCHEMBL14996486 | 0.82 | AVPR1A (0.50) | AVPR1AOPRD1 | |
| SCHEMBL24204169 | 0.82 | AVPR1A (0.45) | AVPR1A | |
| SCHEMBL30447418 | 0.82 | AVPR1A (0.45) | AVPR1A | |
| SCHEMBL31059162 | 0.82 | AVPR1A (0.39) | AVPR1ASIGMAR1 | |
| SCHEMBL23304985 | 0.82 | AVPR1A (0.39) | AVPR1ASIGMAR1 | |
| SCHEMBL25307002 | 0.79 | AVPR1A (0.40) | AVPR1ASIGMAR1 | |
| SCHEMBL30527669 | 0.79 | AVPR1A (0.40) | AVPR1ASIGMAR1 | |
| SCHEMBL3247835 | 0.77 | AVPR1A (0.47) | AVPR1ASIGMAR1CCNCCDK8HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182299-A2 | CYCLIC CYANOENONE DERIVATIVES AS MODULATORS OF KEAP1 | Merck Sharp & Dohme LLC (US) | 2023-05-24 | — | — | EP | disclosed |