SCHEMBL25307002

SCHEMBL25307002

c1cc2c(cn1)C1(CNC1)OC2

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 2/20 0.40
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527669 1.00 AVPR1A (0.40) AVPR1ACHRNB2CHRNA4SIGMAR1
SCHEMBL23304985 0.85 AVPR1A (0.39) AVPR1ACHRNB2CHRNA4SIGMAR1
SCHEMBL31059162 0.85 AVPR1A (0.39) AVPR1ACHRNB2CHRNA4SIGMAR1
SCHEMBL485825 0.83 AVPR1A (0.43) AVPR1ACHRNB2CHRNA4
Hydrochloric Acid SCHEMBL1003364 0.82 AVPR1A (0.43) AVPR1ACHRNB2CHRNA4
SCHEMBL30447448 0.79 AVPR1A (0.42) AVPR1ASIGMAR1
SCHEMBL14996486 0.76 AVPR1A (0.50) AVPR1A
SCHEMBL24204169 0.76 AVPR1A (0.45) AVPR1A
SCHEMBL30447418 0.76 AVPR1A (0.45) AVPR1A
SCHEMBL23304803 0.74 CHRNB2 (0.38) AVPR1ACHRNB2CHRNA4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A AVPR1A 2684/4885CHRNB2 4847/4885CHRNA4 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.