Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173302 | 0.81 | L3MBTL1 (0.47) | L3MBTL1MAPTCNR2CNR1ACHE | |
| SCHEMBL7115402 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MAPTCNR2CNR1ACHE | |
| SCHEMBL30628634 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MAPTCNR2CNR1ACHE | |
| SCHEMBL26630273 | 0.77 | MAPT (0.51) | L3MBTL1MAPTCNR2CNR1ACHE | |
| SCHEMBL26630291 | 0.77 | MEN1 (0.51) | L3MBTL1MAPTCNR2CNR1ACHE | |
| SCHEMBL29508910 | 0.76 | ELANE (0.47) | L3MBTL1MAPTCNR2MEN1KMT2A | |
| SCHEMBL29508852 | 0.76 | ELANE (0.47) | L3MBTL1MAPTCNR2MEN1KMT2A | |
| SCHEMBL1457094 | 0.76 | ELANE (0.47) | L3MBTL1MAPTCNR2MEN1KMT2A | |
| SCHEMBL2871012 | 0.74 | ELANE (0.50) | L3MBTL1MAPTCNR2MEN1KMT2A | |
| SCHEMBL21093059 | 0.73 | MAPT (0.57) | L3MBTL1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463150-A1 | HETEROARYL COMPOUNDS AS HPK1 INHIBITORS AND METHODS OF USING SAME | Shenzhen Ionova Life Science Co., Ltd. (CN) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023137406-A1 | HETEROARYL COMPOUNDS AS HPK1 INHIBITORS AND METHODS OF USING SAME | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2023-07-20 | — | — | WO | disclosed |