Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600488 | 0.79 | MAPT (0.83) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL155568 | 0.79 | MAPT (0.83) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28977297 | 0.76 | MAPT (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL29539965 | 0.75 | MAPT (0.85) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL148001 | 0.75 | MAPT (0.85) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9541803 | 0.73 | CYP1A2 (0.44) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL30447496 | 0.73 | L3MBTL1 (0.45) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28866731 | 0.73 | MAPT (0.54) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL150552 | 0.72 | MAPT (1.00) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL30013273 | 0.72 | MAPT (0.66) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10314816-B2 | Antimicrobial compounds, compositions and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10314816-B2 | Antimicrobial compounds, compositions and methods of use thereof | CLPP, ATP5ME, PCNA | MAPT 4759/4885MEN1 4543/4885KMT2A 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.