Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 11/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ACLY | P53396 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.55 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228439 | 1.00 | MCL1 (0.72) | MCL1LMNAALDH1A1ACLYKDM1A | |
| SCHEMBL10840713 | 0.88 | MCL1 (0.57) | MCL1LMNAALDH1A1ACLYKDM1A | |
| SCHEMBL15228509 | 0.86 | MCL1 (0.70) | MCL1LMNAALDH1A1KDM1ASMN1; SMN2 | |
| SCHEMBL22441753 | 0.85 | MCL1 (0.66) | MCL1LMNAALDH1A1ACLYPOLB | |
| SCHEMBL10801563 | 0.83 | MCL1 (0.63) | MCL1CCR2 | |
| SCHEMBL1138972 | 0.82 | MEN1 (0.57) | MCL1LMNAALDH1A1ACLYKDM1A | |
| SCHEMBL18298893 | 0.82 | LMNA (0.57) | MCL1LMNAALDH1A1ACLYKDM1A | |
| SCHEMBL10622385 | 0.81 | MEN1 (0.66) | MCL1LMNAACLYCCR1CCR2 | |
| SCHEMBL22441699 | 0.80 | MCL1 (0.56) | MCL1LMNAALDH1A1ACLYKDM1A | |
| SCHEMBL21865887 | 0.80 | ALDH1A1 (0.55) | MCL1LMNAALDH1A1ACLYKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472063-A | Targeted conjugates comprising modified siRNAs | 阿布特斯生物制药公司 | 2023-07-21 | — | — | CN | disclosed |