Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.43 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
| ▸ | DUSP4 | Q13115 | 1/20 | 0.41 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137719 | 1.00 | EGLN1 (0.48) | EGLN1F9NPC1NR4A2RAB9A | |
| SCHEMBL17137754 | 0.86 | EGFR (0.49) | F9NPC1RAB9AQPCTIGF1R | |
| SCHEMBL30450030 | 0.82 | EGLN1 (0.48) | EGLN1F9NR4A2 | |
| SCHEMBL17137537 | 0.82 | EGLN1 (0.48) | EGLN1F9NR4A2 | |
| SCHEMBL17137741 | 0.81 | EGLN1 (0.48) | EGLN1F9NR4A2 | |
| SCHEMBL30450790 | 0.81 | EGLN1 (0.48) | EGLN1F9NR4A2 | |
| SCHEMBL17137751 | 0.76 | MAOB (0.50) | F9NR4A2QPCTLPRMT5 | |
| SCHEMBL2096521 | 0.75 | MMP12 (0.55) | QPCTLQPCTLMNA | |
| SCHEMBL2096516 | 0.75 | QPCT (0.42) | QPCTLQPCTPRMT5WDR77 | |
| SCHEMBL22418755 | 0.73 | QPCT (0.47) | NPC1RAB9AQPCTLQPCTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11618744-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11618744-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | P4HA1, PAH, EGLN3 | EGLN1 8/4885F9 4377/4885NPC1 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.