Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014971 | 1.00 | KCNH2 (0.57) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL30451554 | 0.89 | KCNH2 (0.63) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL29014967 | 0.89 | KCNH2 (0.63) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL29014972 | 0.87 | KCNH2 (0.54) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL29015012 | 0.84 | KCNH2 (0.71) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL30450585 | 0.84 | KCNH2 (0.71) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL29014998 | 0.82 | KCNH2 (0.62) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL30451069 | 0.82 | KCNH2 (0.62) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL30450950 | 0.80 | KCNH2 (0.60) | KCNH2KMT2ANPSR1LMNAHTT | |
| SCHEMBL29015021 | 0.80 | KCNH2 (0.60) | KCNH2KMT2ANPSR1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253687-A | Diaryl pyrimidine compound and preparation method and application thereof | 复旦大学 | 2023-06-13 | — | — | CN | disclosed |