Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA7 | P43166 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 5/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37983114 | 1.00 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9450650 | 0.91 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11749015 | 0.91 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13179070 | 0.89 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3358074 | 0.89 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL321387 | 0.89 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29843135 | 0.89 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31194402 | 0.86 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL571193 | 0.86 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1687031 | 0.86 | CA12 (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731758-A | Foamable flame-retarding polyester capable of being used for supercritical CO2 and preparation method and application thereof | Lanhai yongle jiangsu new material co ltd | 2012-10-17 | — | — | CN | claimed |
| CN-102492124-A | Alcohol in-situ modified high melt strength polyester capable of being used for carbon dioxide foaming, and preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-06-13 | — | — | CN | claimed |
| CN-102492123-A | Method for preparing polyester with high melt strength for foaming CO2 by polyprotic acid in-situ modification and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-06-13 | — | — | CN | claimed |
| CN-102731758-A | Foamable flame-retarding polyester capable of being used for supercritical CO2 and preparation method and application thereof | Lanhai yongle jiangsu new material co ltd | 2012-10-17 | — | — | CN | disclosed |
| CN-102492124-A | Alcohol in-situ modified high melt strength polyester capable of being used for carbon dioxide foaming, and preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |
| CN-102492123-A | Method for preparing polyester with high melt strength for foaming CO2 by polyprotic acid in-situ modification and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-06-13 | — | — | CN | disclosed |
| US-7687645-B2 | Intermediates for the preparation of citalopram and escitalopram | H. LUNDBECK A/S (DK) | 2010-03-30 | — | — | US | disclosed |
| CN-101362743-A | Intermediates for the preparation of citalopram and escitalopram | LUNDBECK & CO AS H (DK) | 2009-02-11 | — | — | CN | disclosed |
| US-20080058536-A1 | Intermediates for the preparation of citalopram and escitalopram | H. LUNDBECK A/S (DK) | 2008-03-06 | — | — | US | disclosed |
| CN-1761659-A | Intermediates for the preparation of citalopram and escitalopram | LUNDBECK & CO AS H (DK) | 2006-04-19 | — | — | CN | disclosed |
| EP-1611118-A2 | INTERMEDIATES FOR THE PREPARATION OF CITALOPRAM AND ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004083197-A2 | INTERMEDIATES FOR THE PREPARATION OF CITALOPRAM AND ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058536-A1 | Intermediates for the preparation of citalopram and escitalopram | SLC6A4, HTR4, HTR3C | CA12 2150/4885CA1 2241/4885CA2 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.