SCHEMBL30450986

SCHEMBL30450986

CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)CC

nearest known ligand 0.76

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.57
▸ GNPAT O15228 1/20 0.52
▸ PTPN1 P18031 2/20 0.51
▸ PSEN1 P49768 3/20 0.51
▸ PSEN2 P49810 3/20 0.51
▸ APH1B Q8WW43 3/20 0.51
▸ NCSTN Q92542 3/20 0.51
▸ APH1A Q96BI3 3/20 0.51
▸ PSENEN Q9NZ42 3/20 0.51
▸ GHSR Q92847 1/20 0.51
▸ FURIN P09958 1/20 0.49
▸ PTPN2 P17706 1/20 0.49
▸ CTSD P07339 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438956 0.97 F2 (0.55) F2GNPATPTPN1PSEN1PSEN2
SCHEMBL29611822 0.93 F2 (0.61) F2GNPATPTPN1PSEN1PSEN2
SCHEMBL30450371 0.91 F2 (0.57) F2GHSRCTSD
SCHEMBL30120656 0.90 GNPAT (0.58) F2GNPATPSEN1PSEN2APH1B
SCHEMBL29611454 0.86 PTPN1 (0.60) F2PTPN1
SCHEMBL30063477 0.86 F2 (0.53) F2CTSD
SCHEMBL29429777 0.86 GHSR (0.56) F2GHSR
SCHEMBL29611881 0.86 F2 (0.59) F2PTPN1
SCHEMBL4927118 0.86 FURIN (0.60) GNPATPTPN1GHSRFURINPTPN2
SCHEMBL29611951 0.85 BACE1 (0.54) GNPATPTPN1GHSRFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590121-B2 Peptide compound with repetitive sequences UNIV KING ABDULLAH SCI & TECH (SA) 2026-03-31 — — US disclosed
US-12116421-B2 Peptide-based Dopa containing adhesive gels KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2024-10-15 — — US disclosed
US-20230374069-A1 PEPTIDE-BASED DOPA CONTAINING ADHESIVE GELS KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2023-11-23 — — US disclosed
EP-4200313-A1 PEPTIDE COMPOUND WITH REPETITIVE SEQUENCES King Abdullah University Of Science And Technology (SA) 2023-06-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590121-B2 Peptide compound with repetitive sequences MEF2D, VIP, IGFBP4 F2 893/4885GNPAT 4104/4885PTPN1 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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