Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 9/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25303127 | 0.92 | ALDH1A1 (0.56) | ALDH1A1CYP2D6PIK3CDCSNK1DDYRK1A | |
| SCHEMBL30450142 | 0.92 | ALDH1A1 (0.56) | ALDH1A1CYP2D6PIK3CDCSNK1DDYRK1A | |
| SCHEMBL25834262 | 0.92 | ALDH1A1 (0.56) | ALDH1A1CYP2D6PIK3CDCSNK1DDYRK1A | |
| SCHEMBL25259089 | 0.87 | PIK3CD (0.50) | CYP2D6PIK3CDLCKCSNK1DDYRK1A | |
| SCHEMBL31114491 | 0.87 | PIK3CD (0.50) | CYP2D6PIK3CDLCKCSNK1DDYRK1A | |
| SCHEMBL30450379 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CSNK1DDYRK1APOLB | |
| SCHEMBL25307365 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CSNK1DDYRK1APOLB | |
| SCHEMBL25300056 | 0.78 | ALDH1A1 (0.67) | ALDH1A1CYP2D6CSNK1DDYRK1A | |
| SCHEMBL30451396 | 0.78 | ALDH1A1 (0.67) | ALDH1A1CYP2D6CSNK1DDYRK1A | |
| SCHEMBL25833329 | 0.78 | ALDH1A1 (0.67) | ALDH1A1CYP2D6CSNK1DDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460500-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |