Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.76 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001887 | 1.00 | PGR (0.76) | PGRMAOAMAOBPLA2G2APLA2G4A | |
| SCHEMBL6244641 | 0.86 | PGR (1.00) | PGRCYP19A1CA12CA1CA2 | |
| SCHEMBL15842362 | 0.81 | PGR (0.77) | PGRMAOAMAOBCYP19A1CA12 | |
| SCHEMBL3362663 | 0.79 | TDP1 (0.61) | PGRMAOAMAOBCA12CA1 | |
| SCHEMBL30450770 | 0.79 | TDP1 (0.61) | PGRMAOAMAOBCA12CA1 | |
| SCHEMBL30588914 | 0.79 | TDP1 (0.61) | PGRMAOAMAOBCA12CA1 | |
| SCHEMBL2724557 | 0.78 | ESR1 (0.58) | PGR | |
| SCHEMBL1987912 | 0.78 | ESR1 (0.58) | PGR | |
| SCHEMBL30703158 | 0.78 | ESR1 (0.58) | PGR | |
| SCHEMBL31035850 | 0.78 | TDP1 (0.59) | PGRMAOAMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116135848-A | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| CN-116135848-B | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-03-12 | — | — | CN | disclosed |
| CN-116135848-A | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2023-05-19 | — | — | CN | disclosed |